• Mars 1845. Henri David Thoreau est revenu à Concord, Massachusetts, son village natal. Endeuillé par la mort de son frère, lassé des grandes villes et d'une société trop rigoriste pour le laisser pratiquer l'enseignement tel qu'il l'entendait, le poète philosophe a choisi de revenir à une vie simple, proche de la nature, entre les quatre murs qu'il s'est bâti. C'est dans ce cadre qu'il écrira les essais qui feront de lui une des figures marquantes du XIXe siècle américain, dont les idées trouvent encore un écho, chaque jour plus actuel.
    Après Nietzsche, Maximilien Le Roy nous prouve une nouvelle fois combien la philosophie d'un homme est intimement liée à sa biographie. Une plongée dans la vie et la pensée d'un philosophe américain majeur !
    Mars 1845. Henri David Thoreau, lassé des grandes villes et d'une société trop rigoriste pour le laisser pratiquer l'enseignement tel qu'il l'entend, le poète philosophe choisit de revenir à une vie simple, proche de la nature, dans son village natal. C'est dans ce cadre qu'il écrit les essais qui feront de lui une des figures marquantes du XIXe siècle américain, dont les idées trouvent plus que jamais un écho aujourd'hui.

  • Gastrointestinal Emergencies 3E provides practical, up-to-date guidance for gastroenterologists, endoscopists, surgeons, emergency and acute physicians, medical students and trainees managing patients presenting with GI complications and/or emergencies. Combining a symptom section, a specific conditions section and a section that examines complications (and solutions) of GI procedures, focus throughout is on clear, specific how-to guidance, for use before a procedure or immediately after emergency stabilization.  An evidence-based approach to presentation, diagnosis and investigation is utilized throughout. New to this third edition are several brand new chapters covering various complications of procedures and specific conditions not previously featured, as well as a thorough look at the many diagnostic and therapeutic advances in recent years.  In addition, every chapter from the current edition has undergone wholesale revision to ensure it is updated with the very latest in management guidelines and clinical practice.  Once again, full range of emergencies encountered in daily clinical practice will be examined, such as acute pancreatitis, esophageal perforation, capsule endoscopy complications, acute appendicitis, and the difficulties after gastrointestinal procedures. International guidelines from the world's key gastroenterology societies will be included in relevant chapters. Gastrointestinal Emergencies 3E is the definitive reference guide for the management of gastrointestinal emergencies and endoscopic complications, and the perfect accompaniment for the modern-day gastroenterologist, surgeon, emergency and acute physicians. Every Emergency Department, GI/endoscopy unit, medical/surgical admission unit should keep a copy close at hand for quick reference. 

  • Molecular diagnostics are increasingly used to help guide targeted therapy in solid organ tumors and hematologic malignancies. A large proportion of molecular testing is performed on limited-volume samples obtained via minimally invasive techniques, such as fine needle aspiration. Increasingly, cytopathologists play an essential role in this process, both in the triage of specimens during rapid on-site evaluation and in the evaluation of archival samples to determine suitability for ancillary testing. Therefore, it is imperative that practicing cytopathologists stay abreast of up-to-date diagnostic, prognostic, and predictive ancillary tests that can be used on limited cytologic material. This is a challenge since the landscape of known genomic alterations is constantly evolving and the subsequent set of testing options is ever expanding.
    The proposed text will provide a user-friendly quick-reference handbook to serve as a useful resource for practicing pathologists and laboratory personnel dealing with, and interested in, this evolving field of molecular cytopathology. Essential components to be presented include: 1) pre-analytic factors that affect sample selection and evaluation; 2) specimen preparation to maximize confidence in results; 3) interpretation of results; 4) potential limitations; and 5) workflow algorithms.  In addition, specific disease specific molecular testing details will be outlined to provide the reader with resources for quick reference. All chapters will be written by experts in their fields and will include the most up-to-date scientific and clinical information.
    Molecular Diagnostics in Cytopathology will be of value to Cytopathologists, Cytotechnologists, Cytotechnology students, Cytopathology fellows, Surgical pathologists, Pathology residents and fellows, Molecular Pathologists, Molecular pathology fellows, Molecular technologists, as well as  Translational researchers with an interest in molecular cytopathology.

  • Explores key challenges and solutions to assured cloud computing today and provides a provocative look at the face of cloud computing tomorrow This book offers readers a comprehensive suite of solutions for resolving many of the key challenges to achieving high levels of assurance in cloud computing. The distillation of critical research findings generated by the Assured Cloud Computing Center of Excellence (ACC-UCoE) of the University of Illinois, Urbana-Champaign, it provides unique insights into the current and future shape of robust, dependable, and secure cloud-based computing and data cyberinfrastructures. A survivable and distributed cloud-computing-based infrastructure can enable the configuration of any dynamic systems-of-systems that contain both trusted and partially trusted resources and services sourced from multiple organizations. To assure mission-critical computations and workflows that rely on such systems-of-systems it is necessary to ensure that a given configuration does not violate any security or reliability requirements. Furthermore, it is necessary to model the trustworthiness of a workflow or computation fulfillment to a high level of assurance. In presenting the substance of the work done by the ACC-UCoE, this book provides a vision for assured cloud computing illustrating how individual research contributions relate to each other and to the big picture of assured cloud computing. In addition, the book: Explores dominant themes in cloud-based systems, including design correctness, support for big data and analytics, monitoring and detection, network considerations, and performance Synthesizes heavily cited earlier work on topics such as DARE, trust mechanisms, and elastic graphs, as well as newer research findings on topics, including R-Storm, and RAMP transactions Addresses assured cloud computing concerns such as game theory, stream processing, storage, algorithms, workflow, scheduling, access control, formal analysis of safety, and streaming Bringing together the freshest thinking and applications in one of today's most important topics, Assured Cloud Computing is a must-read for researchers and professionals in the fields of computer science and engineering, especially those working within industrial, military, and governmental contexts. It is also a valuable reference for advanced students of computer science. 

  • The book presents an empirical model of commonly occurring individual differences in children that is derived from a large-scale research effort assessing parental and teacher perceptions of children in middle childhood. It examines eight characteristic behavioral traits, most of which have been widely shown to be present in infants, toddlers, and preschool-aged children. The book demonstrates the importance of considering profiles of these relatively stable individual differences for the educational, social, and emotional life of the child. It describes characteristic behaviors of children within each profile - emphasizing the assets and liabilities of each - and how they are perceived by their parents, teachers, and peers. Chapters explore issues related to the most developmentally effective management of children exhibiting each profile type.In addition, the book addresses a critical need in child development, parenting, and teaching to understand the wide range of individual differences observed every day in school-aged children. Not only does this volume underscore that commonly occurring differences can be understood as being normal and do not suggest a pathology, it also discusses implications of the model in diagnosing pathology. The book describes what is known about the stability of temperament behaviors and profiles across the lifespan as well as the origins of these behaviors.Key topics addressed include:Nurturing development of well-adjusted children.Causes of individual differences in children's behavior.Temperamental tendencies and profiles of children.Diagnosing psychopathology in children.This book is a must-have resource for researchers, professors, and graduate students as well as clinicians and related professionals in developmental, clinical child and school psychology, social work, public health, pediatrics, family studies, educational psychology and counseling, and all other interrelated disciplines.

  • Casual readers of the title of this book might be forgiven for thinking that it is a little esoteric, far-removed from the pressing day-to-day concerns of humans and wildlife in the drylands of the world. But they could not be more wrong. It addresses an issue of the utmost practical importance in the world today, yet does so on the basis of exciting new theory about how the world operates. Of the billion or so human beings who now live in the world's arid and semi-arid lands, a majority depend on natural resources for their livelihoods. These natural resources include livestock and their forage, as well as the wild biota that creates opportunities for tourism or subsistence harvesting. Arid and semi-arid lands are spread over a third of the world's land surface, from Colorado to the Kalahari, the Sahel to the Simpson, the Altai Steppe to Amboseli. Notwithstanding their diversity, these lands are broadly cha- cterised by low productivity, management at large scales, and great climate variability - in short, by high spatial and temporal heterogeneity. This book is about the implications of that high spatial and temporal heterogeneity for life, management and policy in arid and semi-arid lands.

  • The essays that comprise this volume clearly demonstrate that coalitions have dramatically altered the shape of war. Paul Kennedy's overview of coalitions over the past century shows that, with coalitions firmly established as viable in the minds of strategists, wars have become markedly lengthier, bloodier, and much more expensive. Three of the essays focus on explicitly military aspects of the two world wars: Norman Stone's on the Austro-German Alliance, 1914-18; Ulrich Trumpener's on the German-Ottoman Coalition, 1914-18; and Ian Nish's on the Greater East Asian Co-prosperity Sphere. J. L. Granatstein pursues a contrasting, though equally enlightening, course, focussing on Hume Wrong, the "functional principle," and the difficulties inherent in Canada's role in the diplomacy of the post-World War II era. In keeping with the immediacy of Granatstein's concerns is John Erickson's lucid presentation of Soviet military philosophy, a matter of crucial and immediate concern.

    This book will be of interest to military historians,
    political scientists, and the more general reader intrigued
    by military history and philosophy.

    These essays, edited and compiled by Keith Neilson and Roy Prete, who teach in the Department of History at the Royal Military College, Kingston, were presented at the Eighth Royal Military College Military History Symposium.

  • Indhold: Military Occupations: Some Reflections from Recent and More Distant History( Hugh Seton-Watson); The British Army of Occupation in the St. Lawrence Valley 1760-74: The Conflict Between Civil and Military Society(Fernand Ouellet); The Regime du Sabre-West African Style: The French Marines in the Western sudan, 1880-99(A.S.Kanya-forstner); Whites and Reds in South Russia, 1917-20(Peter Kenez); The German Occupation of Poland During the First and Second World Wars: A Comparison(Antony Polonsky); The German Occupation of Norway in World War II(Olav Riste); The American Occupation of Japan, 1945-52(Gordon Daniels).

  • Comment parler de cinéma sans en venir un jour à aborder le territoire de tous les spectres et fantômes qui le hantent ? Ce numéro de 24 images s'attaque à la grande diversité des modes d'apparition fantomatique dont est chargée l'histoire du cinéma. Qu'il s'agisse de films hantés par d'autres films (le spectre de Louis Feuillade; le cinéma de Jesús Franco), de films de fantômes (la tradition asiatique et l'oeuvre de Kioyoshi Kurosawa), de films hantés par l'Histoire (Godard, Fassbinder, Nicolas Klotz et Élisabeth Perceval), ou de la pratique expérimentale du found footage (Apitchatpong Weerasethakul), nombreuses sont les ombres qui hantent l'image cinématographique. Des analyses des oeuvres de Buñuel, Hitchcock et Tourneur complètent ce dossier ponctué d'images évocatrices et poétiques. Le DVD du film Que ta joie demeure de Denis Côté accompagne cette édition.

  • This book provides essential information on Mexico's Holocene and Anthropocene climate and vegetation history. Considering the geography of Mexico - which is home to a variety of climatic and environmental conditions, from desert and tropical to high mountain climates - this book focuses on its postglacial paleoecology and paleoclimatology. Further, it analyses human intervention since the middle Holocene as a major agent of environmental change. Offering a valuable tool for understanding past climate change and its relationship with present climate change, the book is a must-read for botanists, ecologists, palaeontologists and graduate students in related fields.

  • Comment construire un système de santé mieux adapté à la multiplication des contraintes et plus performant ? Des réseaux responsables de leur population ne se contente pas d'aborder cette question d'importance : à la faveur d'une réflexion remarquable, il nous offre un corpus de propositions et de pistes novatrices pour une modernisation de la gestion et de la gouvernance en santé.

    Présenté sous une forme précise et accessible, agrémenté de tableaux et de schémas éclairants, Des réseaux responsables de leur population constitue un ouvrage de référence essentiel à toute personne impliquée dans la construction, la gestion ou la gouvernance des systèmes de santé, et à tout public désireux de suivre la direction empruntée par les organisations destinées à le servir.

  • Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology. 

  • The Wiley-Interscience Paperback Series consists of selected books that have been made more accessible to consumers in an effort to increase global appeal and general circulation. With these new unabridged softcover volumes, Wiley hopes to extend the lives of these works by making them available to future generations of statisticians, mathematicians, and scientists. "The title of the book more or less sums up the contents. It appears to me to represent a real breakthrough in the art of dealing in `unconventional' data. . . . I found the whole book both readable and enjoyable. It is suitable for data analysts, academic statisticians, and professional software writers."
    -Journal of the Royal Statistical Society "The book assumes a working knowledge of all of the principal results and techniques used in least squares multiple regression, as expressed in vector and matrix notation. Given this background, the book is clear and easy to use. . . . The techniques are illustrated in great detail with practical data sets from econometrics."
    -Short Book Reviews, International Statistical Institute Regression Diagnostics: Identifying Influential Data and Sources of Collinearity provides practicing statisticians and econometricians with new tools for assessing quality and reliability of regression estimates. Diagnostic techniques are developed that aid in the systematic location of data points that are unusual or inordinately influential; measure the presence and intensity of collinear relations among the regression data; and help to identify variables involved in each and pinpoint estimated coefficients potentially most adversely affected. The book emphasizes diagnostics and includes suggestions for remedial action

  • Cultivate self-awareness, empathy, and clinical competence in the mental health professionals you supervise Providing tested guidance for clinical supervisors of mental health professionals, editors Roy A. Bean, Sean D. Davis, and Maureen P. Davey draw from their own backgrounds in training, private practice, and academe, as well as from an international panel of experts representing various mental health fields to provide activities and best practices that allow therapists to better serve an increasingly diverse set of clients and issues. While clinical skills are easily observed, the more subtle areas of self-awareness, or exploring unexamined judgments are more difficult to spot and to provide supervision and guidance for. The numerous experiential activities included will help supervisors and the mental health professional they supervise develop their skills and techniques around: Intuition Empathy Self-awareness Mindfulness Multicultural awareness Perspective taking The book covers both clinical as well as diversity-focused competence and awareness, and suggests various forms of activities, including research exercises, reflection, journaling, and more. Each activity includes measurement metrics as well as additional resources that help clinicians identify the best activity for a given situation. Appropriate for clinicians at every level and from a multitude of backgrounds, these tried and tested best practices can be used in clinical supervision, as a class assignment, or to facilitate professional growth.

  • Written by more than 60 international experts in the field, Muscle Disease embodies the explosion of new concepts and information on the pathology and genetics of muscle disease that has occurred in recent years. In order to accommodate the new complex principles involved, the book is organized around the motor unit and the inherited disorders, in particular, are centered on the ultrastructure and organelles within the muscle fiber.  In this way, the wide spectrum of muscle diseases, ranging from neurogenic and inflammatory disorders to those involving defects in a single gene, can be expressed in a logical sequence.  For example, disorders that principally involve specific organelles or particular metabolic processes are grouped together, with sections on disorders of the sarcolemma, mitochondria, myofibrils, glycogen and lipid metabolism, etc.  Firm reference to clinical aspects and classification of muscle diseases has been maintained throughout the book with an initial clinical overview and with specific clinical sections in each chapter.  For ease of navigation through the complex variety of muscle diseases, each chapter has been organized in a standard pattern that allows the reader to easily locate information on individual disease entities in different chapters. This new edition of Muscle Disease: Pathology and Genetics will be a very valuable resource for clinicians, pathologists, geneticists and basic neuroscientists involved in diagnosis, research, treatment and management of patients with muscle disease.